The present study was conducted with the aim of designing and validating a digital transformation model with a sustainability-based innovation approach in the food packaging industry. This study is a cross-sectional survey study from the perspective of an applied-developmental objective and a cross-sectional survey study in terms of data collection method. A mixed exploratory research design was used to achieve the goal. The qualitative participant population included managers, experts, and specialized personnel in the food packaging industry. Sampling was conducted using a purposive method and theoretical saturation was achieved with 20 interviews. In the quantitative part, the perspective of 150 managers and experts in the food packaging industry was used. The sample size was determined using the effect size and power test method, and the cluster-random method was used for sampling. The data collection tool was a semi-structured interview and a researcher-made questionnaire. The data analysis method was used for data analysis with Maxqda software, and for leveling, structural-interpretive modeling with Micmac software, and for validation, partial least squares with Smart PLS software was used. The results of the research showed that the designed model was identified with 14 components: business resources, digital transformation leadership, digital/sustainable foresight, digital/sustainable strategies, application of new technologies in processes and operations, digital/sustainable key capabilities, digital employee experience, a new approach to innovative processes in the food packaging industry, improving sustainable food packaging practices, designing innovative food packaging, aligning digital/sustainable innovation strategy with digital/sustainable capabilities, business sustainability in the digital age, improving customer experience (digital/sustainable), and implications in the food packaging industry.