This research aims to address the challenge of universities in commercializing technology and strengthen cooperation between universities and industry, presenting a comprehensive model for technology transfer from universities to industry. The research method is a mixed method, which is applied in terms of purpose and exploratory in nature. The statistical population in the qualitative section was articles in the field of technology transfer and academic commercialization published in the two databases Scopus and Web of Science from 2013 to 2023. The data collection tool was a systematic review of previous studies, selection of articles based on the criteria of the PRISMA method, and the data analysis method was the meta-synthesis method. In the quantitative part, a researcher-made questionnaire and library resources were used to collect data, and its statistical population was Iranian public universities in 1403 and the sampling method was purposive. SPSS and Smart PLS software were used to analyze and evaluate the results. In the qualitative section, first, the environmental factors affecting technology transfer from university to industry were categorized into 5 main categories: "technology supplier characteristics", "technology recipient characteristics", "technology characteristics", "region characteristics", and "laws and regulations". Then, their relationship to each other and to technology transfer methods was evaluated. The results showed that among the identified environmental factors, "laws and regulations" have the greatest impact on the methods of technology transfer from university to industry. Also, "technology characteristic" has a direct effect on "sales-based technology transfer methods", and "technology supplier characteristic" has a direct effect on "consultation-based technology transfer methods". However, the "technology recipient characteristics" and "regional characteristics" do not directly affect the methods of technology transfer.